Saturday, December 30, 2017

Angry Snowman-Naloxone Refusals

 

An older man with a cell phone meets us at the door to the apartment lobby. His hands shake. He motions for us to follow toward the stairs.

“What’s going on?” I ask.

“I just went out for ten minutes and I came back and found him.”

“Is he breathing?” I ask.

But he does not answer. I take the stairs two at a time, carrying my house bag over my shoulder and the monitor in my hand. I can barely keep up with him his steps are so quick. I follow him up to the second floor, and then down a long hallway to an apartment whose door opens into the living room. A large man in a sofa chair leans to the left motionless. I can only see him from behind. I come around the side and see he is blue and not breathing. I grab his arm, expecting to find rigor, but the arm is limber and the man emits an agonal gasp. He has a bounding carotid pulse. He has to be two sixty, muscle shirted with tattoos, I’m guessing late thirties. My partner gets out the ambu bag while I get my med kit from the house bag. I quickly screw the narcan vial into the injector and attach the atomizer. 2 milligrams up the nose, one in each nostril. A oral airway in the mouth. We strap on an ETCO2 cannula. 100. It doesn't get any higher.  He needs ventilation.  Fortunately, he bags easily. I go to put the 02 sat sensor on him, but I have to switch from the left hand to the right. His left hand is missing at the wrist. In no time his sat is 100%, but we are still breathing for him. His ETCO2 is still high in the 80s.

“He’s going to be okay,” I tell his father. “We’re breathing for him now, but he’ll come around. You called in time.”

He doesn’t look like he believes me.

Thirty seconds later, the patient’s end tidal drops to 39 and his chest begins to move. He is no longer blue.

“See, he is breathing on his own now,” I tell the father.

“Found them,” my partner says. He has found the heroin bags in the trash can. In his gloved hand he shows us the bags. They have a blue inked stamped picture of an evil, angry snowman. We’ve seen the brand before.

“Do you have narcan?” I ask the father now, while we wait for his son to come all the way around.

He shakes his head.

“You have to get it.”

“He’s been clean.”

“It doesn’t matter. People relapse. It’s expected. You have to always have Narcan around just in case. It can save his life if we don’t get here quick enough.”

The patient opens his eyes and looks around. “Hey, here we are,” I say. The patient pulls the ETCO2 cannula out of his nose.

“You oded.” I say. “We gave you Narcan. You weren’t breathing.”

“I did not,” he said. “I don’t do drugs.”

“Felix,” the father says to him sternly.

“Look, man,” I say. “Here’s the oral airway we had down in your throat. Here’s our ambu-bag we used to breathe for you. Here’s the Narcan injector. And there are your heroin bags. Snowman, sound familiar?”

“Get out of my house. Leave me alone!” he says. “I know my rights.”

“No, we really should take you to the hospital. What we gave you doesn’t last as long as the heroin, you could od again.”

“I told you. I didn’t use.” He stands now and because of his size he reminds me of a bear on his hind legs. Or maybe an angry snowman. He swats down our suggestions as he stands and points toward the door. “Get out. I know my rights, you can’t trample on my rights.”

I wish I had a picture of what he looked like all blue and slumped over in his chair when we got there to show him. It occurs to me I could have had his father take a picture of him that we could later show him. But then I think he knows he overdosed and he is both in withdrawal now, his high stolen, and angry with us for still being there.

I try to engage him about the potential dangers, warning him he could die. He will not listen to me or his father, who attempts to help.

The fire department responders ask if we want the police called.

I know if we call them, they will come and they will yell at the man who will yell at them. Chests will be puffed out. The message will be go to the hospital or you will be arrested. It is threat that works most of the time. But the truth is the man is within his rights to refuse. He knows where he is, knows the day of the week. When I ask him who is president, he thinks a moment, and then says, “That white prick.”: Everybody laughs. No matter your political views, you have to give him credit for the answer. A man’s entitled to his opinion.

I don’t ask for the cops. If we transport him, he will just leave the hospital AMA as soon as we get there. He is clearly not ready for rehab. And his father will be there to monitor him.

A prudent call to medical control for a high-risk refusal. The doctor reiterates the dangers but agrees if he is alert and oriented,you cannot force him to go.

I tell the patient, “We are going to leave, but you need to listen to me first.”

“No, you need to listen!  I know my rights.  Get the fuck out of my apartment!”

I keep my voice calm, and start going through my harm reduction spiel. I tell him if he is going to use heroin, he must never do it alone. He and his father need to make certain they have Narcan in the house. I tell them where to get it. Go to the needle exchange van or go to a local pharmacy. If you bring your Medicaid card, they will write you a prescription, train you and give it to you for little to no copay. I tell him about Fentanyl, how it clumps so one bag may be relatively mild, the next could contain a fatal dose. I tell him not to mix with benzos. I tell him if he has a period of abstinence, he should start back with a much smaller dose. I tell them if there is a overdose and they call 911, no one will be arrested unless they are dealing drugs.

He won’t look at me, but he is listening.

Finally, I write down the opioid hotline number, which I leave on the kitchen table, and tell the father and the son to not hesitate to call 911 at any time. The father thanks us for saving his son.  He shakes our hands.

“Now get the fuck out of my apartment!” the son says.

And we leave.

***

This is the first refusal I have taken after giving Narcan. I have done many refusals after waking patients up with stimulation. Data I have seen shows that close to 98% of the Naloxone administrations in our city ended up being transported. I don’t have the hospital data on the number of patients who left there AMA, but I suspect it is probably in the 10-15% range.

A 2017 Clinical Toxicology study Do heroin overdose patients require observation after receiving naloxone? concluded:

Patients revived with naloxone after heroin overdose may be safely released without transport to the hospital if they have normal mentation and vital signs. In the absence of co-intoxicants and further opioid use there is very low risk of death from rebound opioid toxicity.

https://www.ncbi.nlm.nih.gov/pubmed/21612385

A 2016 article in Prehospital Emergency Care, Assessing the Risk of Prehospital Administration of Naloxone with Subsequent Refusal of Care, concluded:

The practice of receiving pre-hospital naloxone by paramedics and subsequently refusing care is associated with an extremely low short- and intermediate-term mortality. Despite an evolving pattern of opioid abuse, the results of this study are consistent with previously reported studies.

A 2011 study, No deaths associated with patient refusal of transport after naloxone-reversed opioid overdose published in Prehospital Emergency Care, found that out of five-hundred fifty-two patients who received naloxone and then refused transport, none of them died (as recorded by the medical examiner's office) within the next forty-eight hours.

Despite these studies, you should always do your best to try to get the naloxone-reversed patient to go to the hospital. But in the end, if they are alert and oriented, all you can do is give them a harm reduction talk. Many EMS services even go so far as to leave a naloxone kit. Connecticut is working on a similar protocol.

Here are some other thoughtful discussions of the issue:

‘Treat and Release’ after Naloxone – What is the Risk of Death?

Pro Bono: Naloxone and the Refusal Conundrum

Officials: More OD victims refusing ambulance transport after naloxone revival

Tuesday, December 26, 2017

Chest Wall Rigidity

 

You are called for a seizure in the men’s room at McDonald’s. You arrive to find an approximately thirty-year old man stiff and purple, gurgling.

“Versed?” Your paramedic student says as you break out an ambu-bag.

“Check his pupils.”

“Pinpoint.”

You hand him Naloxone. “Give him 1.2 IM,” you say.

He looks at you like you are testing him.

“Go ahead. Right in the thigh.”

You normally give Naloxone IN, but when the patient is either in full respiratory arrest or in this seizure like state, you like to go IM because it works quicker.  You toss the ambu-bag to a firefighter who has just arrived. It takes him a moment to get the seal. His first breath is ineffective. You take out an oral airway and slip it in his mouth as the tension seems to go away and the man destiffens. His ETCO2 is 100, but gradually comes down to 70, then 60, then quickly drops to 35. In another moment, the man’s eyes are open, and he is looking around in panic.

“You ODed,” you say. “You are in a public restroom. We just gave you narcan.”

“What, I don’t do drugs,” the man says. “I’m fine.”

“Found it,” your partner says. He holds up a orange capped syringe and two torn glassine envelopes labeled Smurf he has removed from the trash can under the sink.

Afterwards, you discuss the call with the student. “How did you know it was an OD?” he asks.

“I’ve seen it several times now,” you say. “I use to think it was a hypoxic seizure, but now I’m not so certain. Have you ever heard of chest wall rigidity?”

He hasn’t. You elucidate.

Chest wall rigidity is a known, but rare side effect of IV fentanyl in the clinical setting. It is most likely caused by pushing large amounts too fast, but it has also been produced by small amounts. The mechanism is not fully understood. The skeletal muscle of the chest wall stiffens and the stiffness can extend into the abdomen, extremities and face. Patients suffering from the syndrome are difficult to ventilate. It has been speculated that the rigidity may extend into the glottis, causing airway obstruction. The syndrome responds to naloxone.

When you first had fentanyl added to your paramedic formulary there was discussion of rigid chest as a side effect, but despite over a decade of pushing fentanyl nearly every shift, and in aliquots of 100 mcgs, sometimes up to a max of 300 mcgs, you have never seen rigid chest syndrome or heard of it happening to another medic.

When you first heard the speculation that illicit drug users might be suffering from it, you poo-pooed it. Even though you have seen the stiffening, it seemed like, and may in fact be, a hypoxic seizure as the brain is deprived of oxygen, except it doesn’t look like the hypoxic seizures you have seen in patients who seized and then went into arrest. This seizure is totally tonic -- rigid muscles with no spasming -- and it persists.

Fentanyl Ads a New Terror for People Abusing Opioids

You research chest wall rigidity. Most of the literature on it is old, but there is a 2013 Clinical Toxicology article that posits the very question you are seeking to answer.

Could chest wall rigidity be a factor in rapid death from illicit fentanyl abuse?

The authors examined 48 fentanyl deaths, and found that an examination of metabolites suggested that at least half of the deaths had been very rapid consistent either with chest wall rigidity or perhaps simply a high enough dose to cause sudden respiratory arrest, followed quickly by death. They cite two prehospital run forms documenting difficulty ventilating until naloxone was given.  It is not a very convincing article -- it is mainly just speculation, but reading some of the sources the author cite was very informative. One was a 1993 study, Fentanyl-induced rigidity and unconsciousness in human volunteers. Incidence, duration, and plasma concentrations, in which 50% of the human volunteers who received fentanyl at a dose of 15 mcg/kg administered at 150 mcg/min. (15 100 mcg vials in 10 minutes for 220 lb). Were observed to develop chest wall rigidity. This is the equivalent of 15 100 mcgs vials of fentanyl -- way more than we would ever give one of our patients.

How much fentanyl are illicit users injecting? Considering a 0.1 gram bag of 50% pure heroin is the equivalent of 10 100 mcg vials of fentanyl, it does not seem unreasonable that illicit users, many of whom inject up to 10 bags at a time, are injecting enough fentanyl to cause chest wall rigidity. While there is very poor quality control from batch to batch even from bag to bag within a batch as fentanyl tends to clump and not mix easily, I have no doubt that some users are suffering from this side effect.

What does it mean for your practice?

Consider opioid overdose in tonically seizing patients who you suspect may be illicit drug users. It is likely a syringe will be in close proximity. (Could it be caused by inhalation as well? At the high doses they are using, it could be possible.) If you have a patient who’s chest seems stiff and you have trouble ventilating, consider naloxone. If the patient is suffering rigid chest syndrome, it should immediately get better.

A lingering question I have is if someone develops rigid chest wall and they arrest, how long after they become asystolic until the rigidity subsides. If the rigidity caused closure of the glottis, will the glottis open on asystole?  Every hypoxic seizure that led to cardiac arrest I have seen, the patient immediately became flaccid. I don’t know if this is the case with chest wall rigidity.  If you have someone you can’t ventilate, consider naloxone. If the chest is too rigid to do CPR (and the rigidity persists) the drug may not circulate and the person may die in spite of your efforts.

 

Sunday, December 17, 2017

Naloxone in Cardiac Arrest

  

Case # 1

You find the fifty year old man supine on the floor with the fire department doing CPR. Their AED announces, “No shock advised. Continue CPR.”

You set your monitor by the man’s head and connect the fire department’s pads to your monitor, while your paramedic student quickly places an IO in the man’s tibia. As you approach the two minute mark, you charge the monitor, and then order stop CPR. The patient is in asystole. “Continue CPR,” you say, as you harmlessly dump the charge by hitting the joule button.

Just then the man’s wife announces, “Oh, my God! He was using heroin.” She holds the empty bags she has just found in the trash can. “He used to use. He’s been clean for five years.”

What drug do you give?

***

Epinephrine.

According to the 2010 AHA Guidelines

There is no data to support the use of specific antidotes in the setting of cardiac arrest due to opioid overdose.

Resuscitation from cardiac arrest should follow standard BLS and ACLS algorithms

Naloxone has no role in the management of cardiac arrest.

Opioids bind to brain receptors that suppress respiration. The patient, if not treated in time, becomes hypoxic and may soon go into cardiac arrest. Giving the patient in asystolic arrest Naloxone will do nothing to restart the patient’s heart. The patient is in the same condition as someone who has suffered an airway obstruction. Hypoxia is the killer. The patient without a heart beat will not be able to breathe on their own without restoration of the heart beat. You are already taking care of the breathing part with your bag-valve mask.  The priority is getting the heart restarted. That is what epinephrine does.   This patient needs good CPR. Ventilation with a bag-valve mask and epinephrine to get his heart started.

***

Case # 2

You are a basic EMT. You find the fifty year old man supine on the floor with the fire department doing CPR. Their AED announces, “No shock advised. Continue CPR.”

Just then the man’s wife announces, “Oh, my God! He was using heroin.” She holds the empty bags she has just found in the trash can. “He used to use. He’s been clean for five years.”

You feel for a pulse, but find nothing. “Continue CPR,” you say.

What do you do next?

***

Naloxone.

Why? Because even though you can’t feel a pulse, the patient may have a hard one to palpate. He may, in fact, just be in respiratory arrest. You can give Naloxone while you provide CPR. If the patient is in a narrow complex rhythm, they may resume breathing on their own. If you are a medic in this situation and you find a pulseless man with a narrow complex rhythm, you should give Naloxone, while continuing to perform CPR.

The AHA Guidelines for BLS state:

Patients with no definite pulse may be in cardiac arrest or may have an undetected weak or slow pulse. These patients should be managed as cardiac arrest patients.

Standard resuscitative measures should take priority over Naloxone administration, with a focus on high-quality CPR (compressions plus ventilation). (Class I, LOE C-EO)

In October 2015, the guidelines were updated to add:

It may be reasonable to administer IM or IN Naloxone based on the possibility that the patient is not in cardiac arrest. (Class IIb, LOE C-EO).

I have had a couple calls this year where I could not feel a pulse in an apneic patient who I suspected of opioid overdose.

We initiated CPR. I had a narrow complex rhythm on the monitor. I gave Naloxone IM, and after several minutes, the patient regained a respiratory drive. We were able to feel pulses and so stopped CPR. In both cases, I suspect the patients simply had weak or hard to palpate pulses in the first place.

Bottom Line: Focus on good CPR and proper BLS/ALS care.   Give epi for cardiac arrest.  Give Naloxone for respiratory arrest. 

***

Considerations:

This is a theoretical scenario, which I will discuss further in a future post on the topic of rigid chest syndrome and illicit fentanyl use.  If the patient in recent cardiac arrest proves difficult or impossible to ventilate  consider Naloxone.  This is on the theory that the the patient is suffering from rigid chest syndrome caused by some combination of a large dose, a fast push or just simply the properties of fentanyl.  Rigid chest syndrome, which is rare in the clinical setting, can cause the glottis to close, making ventilation impossible.  It is uncertain how long after the patient's heart stops beating the rigidity lasts or whether the patient simply becomes flaccid as they do after a hypoxic seizure.  Rigid chest syndrome should respond to Naloxone.

As always, please follow your local medical control treatment protocols and guidelines.

***

For more on the controversies surrounding the use of naloxone in cardiac arrest, read the multiple and excellent columns by Rogue Medic

The Myth That Narcan Reverses Cardiac Arrest

Naloxone and Cardiac Arrest

Monday, November 20, 2017

Wild Wild West

 

There is an anxious crowd on the corner of Hungerford as we come lights and sirens down Park Street.  A woman with tattooed arms waves for us to hurry.   A man is on the ground with a crowd clustered around him.   I can see another man kneeling over his chest. His arms together like he is doing  CPR.  “They hit him twice,”  a bystander says to me.  "Lot of people packing it on this corner."

“He was just walking along and down he went,” another says.

“He gave him four in the right,” the first man says, and then nodding toward a shorter man wearing a Pittsburgh Pirates hat, “and he gave him two in the left.”  

The man on the ground has his eyes open now and starts looking around as the crowd cheers.

“You oded, man,” a man says to him, still holding the syringe with the atomizer on it.

“I did not,” he says.  “What are you all looking?”

“Man, you were out.  I did CPR on you, man.”

“No, I fine,” he says.  “I just fell out.”

“No, man," a man with the 4 mg nasal spray in his hand says.  "You weren’t breathing.  We gave you Narcan, man.”

“No, I’m good I’m good.”

He insists he did not do drugs, but with the crowd's backing, we get him on our stretcher and take him to the hospital.  On the way, he admits he snorted a bag.  This is the second time this week he has oded, he says.

In Tombstone, a man would drop a glass in a bar, and everyone would whip out their six-guns and point it at him.  In Hartford, everyone is also packing.  A man drops down in the street and everyone whips out their narcan.  Just like the wild wild west.

Note: Park and Hungerford is also the twice a day location of the needle exchange van, where in addition to passing out clean needles, they provide narcan training and hand out free kits.  

Saturday, November 11, 2017

Call of Duty

 

“I’m a shit bag,” he says to me.  “I’m supposed to be taking my boy trick or treating tonight.  I can’t fucking believe I did this.  You said I wasn’t breathing?  After all I’ve been through to die like this.  Fuck me.  I’ve got shit for brains.”

The young man got out of jail an hour before.  Thirty days for failure to appear.  He got picked up by some acquaintances, who as a present gave him a bag of heroin to snort.  (“Just one bag,” he says, “and I snorted it.  I’ve never oded before.  And on top of that I’ve been clean for two months.”)

His acquaintances were going to drop him off at his girlfriend’s house.  His girlfriend was going to drive him to his ex-wife’s house.  His ex-wife had agreed to let him take his son trick or treating.  Instead, when he turned blue and stopped breathing, his new buddies dumped him on the ground in front of a hospital – only it wasn’t a hospital with an ED – and then they took off, leaving him on the pavement.  A security guard found him, called 911 and alerted the medical staff inside.

When he came around, I saw the panic in his eyes.  I was just getting out of the ambulance.  Fire had given him 4 of Narcan IN and had just now stopped bagging him.  He was surrounded by a good twenty medical personnel and at least two crash carts.  A nurse stood over him squeezing a bag of D5/ ½ Normal Saline.  But that wasn’t what was scaring him.  He was looking up at the Grim Reaper, a creepy looking clown and at least three ladies with colorful cat faces and whiskers.  The facility was having a Halloween party.

“It’s okay,” I said to him.  “It’s okay.  You oded.  They gave you Narcan.  It’s Halloween.  You’re okay.  You’re all right now.”

We talk on the way to the hospital.  He broke his back and sustained a concussion when his Humvee hit an IED in an ambush.  He came home with a bad painkiller habit that quickly turned to heroin.  He says he detoxed himself two months ago when he couldn’t get into treatment.  When my paramedic student puts electrodes on his chest, the man flinches.  The scar on his chest is a bullet hole.  “Twelve of us went out, only three came back,” he tells us.  "And now I do this stupid shit."

At the ED we give our report to the nurse and her trainee.  In the room, the paramedic student shakes the tearful man’s hand and says, “Thank you for your service.”  So does the tech, the nurse, her trainee, and my partner.  

It's only two in the afternoon.  They'll let him go in a couple hours.  "You may make it yet," I say.

None of these users are shit bags.  They are medical patients fighting a horrible brain disease of addiction that many contracted through no fault of their own.  This guy, like many others, gave our country his best.    Our duty in EMS is to give our best -- to all of our patients.

Opioid abuse crisis takes heavy toll on U.S. veterans

Thursday, November 09, 2017

Grade A

 

The man kneels in the grass next the pickup truck that has its door open. He vomits.  The fire department is standing over him.  “Citizen Narcan found him in the truck passed out, squirted him with two doses and then took off when we got here,” a firefighter tells me. I see the two 4 mg nasal devices in the grass.

“Thank goodness for community narcan,” I say.

The vomiting man, who looks to be in his early fifties, rouses enough that my partner and our paramedic student are able to get him on our stretcher. I do a quick check of the truck to look for bags, but don’t find any. I do find a used syringe under the center fold down console. I find that odd as the fire department told me they also found a syringe. I do another look in the grass and then I see the bags – three fresh white bags sitting on top of the grass. The brand is a new one. "Grade A" stamped in blue.

On the way to the hospital I learn the man is a house painter. He hurt his back a few years ago when he fell off a ladder. He got hooked on the pain pills. Now he does heroin.

I ask him if he just got out of jail or treatment or if he just ended a period of abstinence.

He shakes his head.

“Did you use more than your regular amount?”

“No, the same.”

“You used Grade A before?”

“No, the guy who sold it to me said it was good.”

“Apparently. You need to be careful. All the fentanyl out there, you can catch a hot spot. You were lucky some dude came along and found you and had narcan.”

He doesn’t seem to understand what I am saying.

“Let this be a lesson,” I say. “Never use alone.”

“I wasn’t alone,” he says.

“Huh?”

“My buddy was with me.”

“Your buddy?"  That explains the second syringe.  

“He wasn’t there?”

“No, a passerby found you. He had Narcan. You should always have Narcan with you.”

“I do. I keep it in the console.”

I am beginning to get the picture now. The alleged passerby was his buddy.

“Where’s my wallet?” he asks.  He pats his pants.  “Shit.” He shakes his head.

“At least he called 911,” I say.

***

I see Mark walking along the sidewalk. No doubt he just came out of the bushes at the corner of Park Terrace and Park. There is a dirt circle in the middle of the bushes that is beaten smooth and covered with empty heroin bags, saline vials, and assorted trash. The users sit on milk cartons and shoot up, before reemerging. Mark’s got that light airy walk going and I can tell he’s feeling pretty good. I met him on a 911 call. He was on the nod at a bus stop, and while I was able to wake him up with just stimulation and ended up not transporting him, we had a long talk that morning.  He was in a car accident his first year in college,  and got hooked on pain pills.  Heroin was an easy transition.  He remembers me as saving his life at the bus station that day, which I didn’t do. At least I haven’t yet. He is still using. A couple weeks ago, he told me he has a plan to detox himself  this winter.  He has some suboxone stashed to help him through it, he says.  My partner pulls the ambulance to the side of the road, and Mark comes over to talk.

“There’s a new brand,” he says. “I just tried it. Grade A. Its white powder, fentanyl. Its best shit I’ve had in weeks.”

“We did an OD with it yesterday. Be careful. You still have your Narcan with you.”

“In my bag always,” he says.

“Very good,” I say. “Peace be with you.”

My partner and I laugh as we watch him make his way down the street with the two other users he is with. The three of them look like Monty Python cast members doing slow motion silly walks.

***

A fellow paramedic tells me he did an OD in a neighboring town. Two dudes in a car, out cold in the middle of the road right by the commuter lot on route 4. The cops arrested the driver who the medic was able to wake up with stimulation. The passenger was unresponsive with agonal breathing. He had to bag him and give 2 mg of naloxone. They brought him to the hospital. I ask about the bags, and he shows me a picture he took of them. Three bags of Grade A.

“Popular brand,” I say.

***

I find Grade A wrappers in various spots about town that week, by the pavilion at Pope Park, in the port-o-potty in Putnam Park, outside an apartment on Vine Street where we are responding for a 19-year-old with chest pain when he coughs. Sunday morning, I check the bushes where Mark and the other users like to shoot up. I make noise as I walk down there so I don’t take anyone by surprise. As I expected, Sunday morning with the sun just coming up, there is no one there.  There are many  grade A wrappers, and Rolex and then fewer of others like Back off, Reaper, Spartan Helmet, Coca-Cola and Diesel. I feel like an archaeologist going back in time, weeks are like years in heron users lives. There are other bags there too faded to read.

**

The next week, I see Mark sitting out in front of the Seven-Eleven. I nod to him as I go in. He smiles at me, but he looks miserable. I get myself a green tea with honey and lemon and a package of blueberry Bell Vita crackers. I stop outside.

“How are you this morning?”

“Struggling,” he says.

I give him the crackers and my change from the register. Maybe a dollar-fifty.  "Buy yourself some coffee."

“You didn’t have to.”

“You refusing?”

“No, I’m just saying.”

“I’m just saying too.” I stand looking out at the gray storm clouds rolling. “It’s going to rain all day.”

“Sucks,” he says.

“What’s good out there this week?”

“Nothing,” he says.

“Not even Grade A.”

“No, barely got me high this morning. They increase the cut till its shit. Wasn’t worth my four dollars.”

“Sucks,” I say.

“Teddy got blue New Worlds on Zion Street, but they charged him $5. He said it was worth it.  And he's a cheap mother.”

“Is that your plan for the day?”

“I only have 30 cents and what you gave me.”

“Wish you luck.”

“Thanks, man.”

“You stay safe now.”

“You, too.”

***

He lays curled in fetal position on my stretcher. Fifty-one years old, but he looks seventy.  This is his first time in rehab and the facility is concerned his extremities are cold and his pulse sat is unobtainable. (We get a 100%).   The man tells me he got cancer ten years ago, and while he beat it – he has been in remission for five years -- he ended up addicted to fentanyl. His doctor lost his license two years ago and he has been unable to find another doctor who will write him scripts for his pain. He snorts a bundle (ten bags) of fentanyl a day now. He knows where to go to get fentanyl – he can tell the difference. Heroin doesn’t do anything for him. The brand he was buying last week was Grade A. The week before Rolex. He has a family, but hasn’t seen them for over year. He says he left so they wouldn’t see this side of him. He knows he has to quit if he wants to be a part of their lives again.

I think about asking him more questions, but it seems like just speaking is an effort for him. I dim the ambulance light and let him try to sleep.

***

The next day, I see Mark and he is happy again. "New World is banging, man," he tells me.  "I just got five and some change for my cans at Stop and Shop."  Ten thirty in the morning and it is already seventy degrees.  The sky is blue and the leaves in the trees are orange, red, and yellow.  A perfect day in Hartford.  Winter seems a long way off.

"Stay safe," I say, as he walks off, headed toward Park Street.

 

 

Thursday, November 02, 2017

Fentanyl Safety

 

Finally!

The Federal Government has listened to the experts and released sensible evidenced-based recommendations on safety for first responders when encountering fentanyl and fentanyl analogues, including carfentanil.

Fentanyl Safety for First Responders

The document issued yesterday by the White House National Security Council is the product of their Federal Interagency Working group with collaborative support of groups such as the American College of Emergency Physicians, the American College of Medical Toxicologists and many other reputable organizations.

Gone are the scare tactics that declared that just touching fentanyl can kill you.  There is no more nonsense about delaying care to search for packages from China.  And the recommendation now is to give narcan for opioid toxidrome symptoms, not merely for exposure.  

The document acknowledges that "misinformation and inconsistent recommendations regarding fentanyl have resulted in confusion in the first responder community."

Here are the key points:

Inhalation of airborne powder is MOST LIKELY to lead to harmful effects, but is less likely to occur than skin contact.

Incidental skin contact may occur during daily activities but is not expected to lead to harmful effects if the contaminated skin is promptly washed off with water.

Personal Protective Equipment (PPE) is effective in protecting you from exposure.

Slow breathing or no breathing, drowsiness or unresponsiveness, and constricted or pinpoint pupils are the specific signs consistent with fentanyl intoxication.

Naloxone is an effective medication that rapidly reverses the effects of fentanyl.

Bravo.  

The fact sheet was issued as an appendix to President’s Commission on Combating Drug Addiction final report.

Tuesday, October 31, 2017

Hope

 

The call is for an overdose in the stairwell of the apartment building. Fire has arrived just before us – they have propped the front door open. I enter with my house bag over my shoulder and carrying the cardiac monitor in my right hand. There is no one in the dim lobby to direct me. I go through the door to the ground floor hallway. I see a stairwell to the far right and one to the far left. I take the one to the right. I don’t hear anyone in the stairwell, so I take the stairs two at a time (I am six eight so this is not too hard for me). I get to the top without encountering fire or an overdose. I come out on the fourth floor, and the go down the hall all the way to the far stairwell, and head down taking them only one at a time (I am 59 and my balance is not the best). I am back down on the ground floor with no patient. I have at least caught up with two firefighters who are trying to radio their fellow crew members to see if they have found anything. I head back up the stairs, stopping on each floor to look and listen. Finally, on my way back down, a door opens on the second floor and a man waves us in. 

The girl is sprawled on the couch. A firefighter is there with her, bagging her. He has given her 4 mg IN, but she is still not breathing on her own other than an occasional gasp. I put her on the ETCO2 and her number is 60, but the number quickly drops to 40 before I can get my Narcan out, and she is now breathing better. A little sternal rub and she opens her eyes.

“You overdosed,” the firefighter says.

She shakes her head and slowly sits. “I’m so embarrassed,” she says.

She is in her early thirties and looks striking like the actress Scarlett Johansson, except she has hard miles on her face and she is a heroin addict. The firefighter says she overdosed yesterday too. They found her in a car on Williams Street.

“I am so sorry,” she says. “I was clean for four months and I relapsed yesterday. And here I am again. I’m sorry.”

I notice her boyfriend is also in the room. He is a tall burly man with a beard. He is clearly high on heroin himself. His pupils are pinpoint and he speaks in an odd whispery voice. He is a little unsteady in the knees. He says they are from out of town, but know the person whose apartment we are in. The boyfriend shot her up in the stairwell before they went to the man’s apartment, not wanting to involve him in their addiction. When she stopped breathing he called 911 on his cell phone and then after getting the man to help, they carried her into the man’s apartment. The boyfriend says he bought the drugs in Hartford on Park Street. He shows me the bags. They are blank.

The girl still has her head in her hands. “I have to be at work at 10,” she says.

A police officer is there and wants to know where the syringe is. The boyfriend says he left it in the stairwell. “Where a kid can find it!” the officer says.

“I’m sorry, I panicked. I needed to get her help,” he says.

They go off to find the syringe. The girl stands slowly and walks out of the apartment with us, over to the small elevator which we take slowly to the ground floor where my partner has the stretcher set up.

I am thinking she looks familiar to me. I remember now where I saw her. She overdosed in the Subway bathroom last summer on the “Fastrack” brand. She was on the ground, blue and agonal. We brought her around with Narcan. I remember her being very apologetic then. We had a very good conversation about the brands. She wanted to know which ones were most dangerous (the ones with Fentanyl) so she could avoid them. “Stay away from Fastrack,” I’d told her.

“Lesson learned,” she’d said.

On the way to the hospital, I ask her how she first got involved with opioids. I am expecting her to tell me as so many do that she got into a car accident or was injured somehow and her doctor gave her a six-month prescription to oxycodone and she got hooked. From there it was easy to make the switch over to heroin, which is cheaper and more readily available. Instead she says. “I don’t remember. I’m an addict. I’ve always been an addict. It’s who I am.”

We drive along in silence.

“If I don’t get to work by ten, I am going to lose my job,” she says. She is a waitress at an all-night diner.

It’s six-thirty now. A couple hours in the ED, and she may get out in time.

“Don’t give up hope,” I say.

***

The call is for an overdose in the bathroom of a fast food restaurant. We arrive to a find a stocky bearded man in his thirties in the bathroom, sitting on the toilet, his pants around his legs, he is cyanotic, his head against the wall, mouth open, pinpoint pupils, not breathing but he is warm and has a pounding carotid pulse. He does not respond to stimulation. While my partner gets out the ambu-bag, I take out the Narcan, and instead of attaching an atomizer to the end, I put on a needle and inject 1.2 mg into his bare thigh. I just want to get him back breathing rather than waiting all the extra time, trying to get a decent seal around his beard. Plus, I don’t know how long he has been hypoxic. I am getting ready to put an oral airway in his mouth. He wakes suddenly and looks up with a start to see me standing over him holding the oral airway, my partner with the ambu-bag, and three firefighters.

“You’re in a public bathroom,” I say. “You overdosed. We just gave you Narcan.”

“Overdosed? What are you talking about? I didn’t overdose.”

“You weren’t breathing. We gave you Narcan.”

“I don’t know what you are talking about.”

“You likely did heroin.”

“Heroin, I don’t know what you are talking about.” He looks away from me quickly, his eyes darting about the room, eyelids blinking.

“Stand up and put your pants on.”

“What are you talking about?”

“You are sitting on a toilet.  Your pants are around your ankles. Pull your pants up. The bathroom door’s wide open.  There are people eating.”

He stands with our help, and we get his pants up. “I don’t know why you are all here?”

“Look,you are not in trouble. You weren’t breathing, we gave you a drug that counteracts opioids and now you are talking to us.”

“I don’t do drugs.” He glances furtively toward the open bathroom door. I think if there were not so many people in the bathroom, he might bolt.

“Okay, whatever," I say.  "We are taking you to the hospital.”

“I don’t think that’s necessary.” I think he is hoping we will all go away and he can just leave and forget this episode ever happened.

“The drug we gave you doesn’t last as long as whatever you took.  You could stop breathing again.”

He looks at me a moment, considering.

“We can take you to either Hartford or Saint Fran.”

“Saint Francis,” he said. “But I really don’t understand this.”

 

We get him on the stretcher. On the way out of the restaurant he clicks his car keys. The lights flash in the black Honda Accord parked at the curb.  We get him in the back of the ambulance and get on our way to the hospital. His forehead is beaded with sweat.   hand him an emesis basin when he says he is nauseous. 

“Listen,” I say. "You know where to get Narcan?”

He looks at me, waiting.

“Go to a pharmacy. Are you on Medicaid or do you have insurance?”

He nods.

“Go to a pharmacy. They will write you a prescription. If you are on Medicaid, it’s free. You live with your girlfriend or your family, and they know you have a problem, then need to know where to get it if they find you overdosed.”

He is paying attention.

“You have to be careful with the fentanyl.  You get a bag that has more than it should, next thing you know you wake up on the toilet looking at me.”

His eyes are wet. I think I am getting through.

“Never do it alone, and you make certain you have Narcan. You buy from a new source, you just do a tester shot, you can always do more. If you have to do it by yourself, do it where someone can find you. If you are in a public bathroom, set a timer that will buzz like crazy if you don’t turn it off. Or I know some people will stuff up the sink, and start the water going so it they OD, the overflowing water will alert someone. I’m not telling you to do that, I’m using it as an illustration. If not, then you better hope that like today there was a dude standing outside the bathroom door, needing to take a piss or drop a log, and said something to the manager about the door being locked and no one answering when he knocked.  No dude needing to take a piss, and you wind up dead. When we finally get to you, the Narcan won’t work. You hear what I’m saying?”

“Yeah,” he says.

“Good.” I hand him a card with the state opioid hotline number on it. “Call this number when you’re ready for help."

He takes the card and put it in his shirt pocket.

“It’s a long road, but you can beat this,” I say.

“I think I’m going to throw up,” he says.

“That’s what the emesis bag is for.”

He retches. 

At the hospital, we put him on a bed in the hallway. After I give the report to the nurse, she goes over to him. “I don’t even know why I am here?” he says. “I don’t do drugs.”

Two hours later, we drive past the fast food restaurant. The black Honda Accord is no longer out front.

Somewhere on Park Street a car window rolls down.

Friday, October 27, 2017

Controversies and Carfentanil

 

Great article in the November 2017 edition of the  American Journal of Emergency Medicine about the  controversies surrounding the dangers of carfentanil, fentanyl and other fentanyl analogues.  The physician authors, John B. Cole and Lewis S. Nelson, take the Drug Enforcement Agency (DEA) and the media to task for sensationalizing the dangers to responders of these synthetic opioids.

They write that the DEA guidance that mucosal or dermal absorption of fentanyl can rapidly kill and the DEA video of two officers suffering symptoms following accidental exposure should, based on "real world and foundational" evidence, "be treated with healthy skepticism."  They note that the officers' symptoms are "inconsistent with opioid poisoning."  They also note that "it is unquestionable that both drug user and sellers contact the product on a regular basis without apparent harm."

Last month in Connecticut, the acting head of the DEA, Chuck Rosenberg, speaking at a Yale Law School Opioid Conference, continued to repeat the DEA's party line.

“It will kill you,” Rosenberg said. And for those with no tolerance, Rosenberg warned: “It can kill you to the touch.”

Hartford Courant story

The DEA and the media continue to spread this false information, and the result can lead to responders failing to act quickly to save people whose lives are endangered.  The DEA briefing guide on fentanyl still urges responders to back off when encountering cyanotic patients.

 "Personnel should look for any cyanosis (turning blue or bluish color) of victims, including the skin or lips, as this could be a sign of fentanyl overdose caused by respiratory arrest. Further, before proceeding, personnel should examine the scene for any loose powders (no matter how small), as well as nasal spray bottles, as these could be signs of fentanyl use.  Opened mail and shipping materials located at the scene of an overdose with a return address from China could also indicate the presence of fentanyl, as China‐based organizations may utilize conventional and/or commercial means to ship fentanyl and fentanyl‐related substances to the United States."

"Before proceeding" to take care of a cyanotic patient on the verge of anoxia or death, the DEA wants you to look for packages from China.

On July 26, the Los Angeles Times, in a story about a drug overdose scene, 1 dead, 2 others hospitalized after authorities find white powder in Santa Ana apartment, reported: “A small dose of the odorless white power can be fatal."   The paper records an official describing the police response to an overdose call: “Officers have been trained to “back off” when they come across white powder and an unconscious victim at the scene of a call, he said.”

Fentanyl: A Briefing Guide for First Responders

The Drug Enforcement Agency needs to issue a correction.

American Journal of Emergency Medicine  article contains a graph listing five safety concerns and the "rational for skepticism."  Here are the five concerns:

Inhalational route of exposure

Dermal absorption

Opioid poisoning from scenes with powdered opioids

Canines poisoned and revived with naloxone may be a harbinger of human poisoning

Description of "poisoning" from drug powder in the air from brushing powder off clothes. 

The answers to the concerns are convincing.  For instance, they note that "dermal absorption requires solubized drug and permeation enhancers to reach concerning blood concentrations and rates of absorption are low."  When talking about the comparison of the dangers to dogs and humans, they make the distinction, "Unlike humans, dogs place noses extremely close to objects they smell; dogs also lick their noses after smelling."

The authors also have some fascinating things to say about carfentanil.

People die from opioids, they write, due to induced apnea.  Carfentanil actually produces less apnea when given at its proper dose than many other synthetic opioids.  The deaths from carfentanil come from uncontrolled dosing.  When drug dealers learn to dose it properly, carfentanil deaths should decline.  A harm reduction worker told me that drug dealers may currently avoid carfentanil because there isn’t yet a good way for them to properly dose it.  As heartless as drug dealers may be, it is bad for business to kill twenty customers in a few hours if the batch is not mixed right.  The risk of using carfentanil (multiple murder indictments) currently outweighs the benefit to many drug dealers.

Carfentanil was the drug used in the Moscow theater hostage catastrophe in 2002.  The authors note that while the Russians weaponized the carfentanil for maximum absorption, only 15% of the hostages succumbed.  At a talk I recently attended on EMS provider safety, the speaker, a toxicologist, showed pictures of the event, including ungloved and unmasked responders removing people from the scene.  None of the responders, the speaker pointed out,  reported any ill effects.

The authors also tackle the question of how much naloxone is needed to counteract a carfentanil overdose and they report that animal data suggests that carfentanil should respond to naloxone at traditional dosing levels.  They emphasize the goal of naloxone is not to wake the person up, but simply to restore effective respirations.  I wonder if all the reports of massive doses needed to revive “carfentanil” overdoses are not a combination of the increasing prevalence of IN naloxone with a slower onset, impatience on the part of responders,* multiple response agencies carrying naloxone now all arriving within minutes of each other and each higher level arriving delivering the drug, responders using the end point of consciousness as their target not restoration of respirations, and the self fulfilling idea that carfentanil overdoses require massive amounts of naloxone, so responders are quicker to deliver more doses.

The authors conclude by suggesting instead of thinking of heroin, fentanyl or carfentanil overdoses in specific, we should be categorizing them all as opioid overdoses and treating them in the same way.  For provider safety, they say standard PPE is reasonable.

Controversies and carfentanil: We have much to learn about the present state of opioid poisoning

* Naloxone can take up to 15 minutes to reach full absorption through the atomizer method according to intranasal.net.

Thursday, October 26, 2017

Falsehood Flies

 

“Falsehood flies, and truth comes limping after it, so that when men come to be undeceived, it is too late; the jest is over, and the tale hath had its effect.” - Jonathan Swift

This quote came to me from a respected toxicologist after reading some news accounts of public safety response to possible fentanyl overdose scenes.

The falsehood that just touching fentanyl can kill you has persisted despite the recently published position paper by The American College of Medical Toxicology and the American Academy of Clinical Toxicology that it is not so.

ACMT and AACT Position Statement: Preventing Occupational Fentanyl and Fentanyl Analog Exposure to Emergency Responders

On July 26, the Los Angeles Times, in a story about a drug overdose scene, 1 dead, 2 others hospitalized after authorities find white powder in Santa Ana apartment, reported: “A small dose of the odorless white power can be fatal.  In some cases, just touching the powder could trigger an overdose like it did this year in Ohio.”  They go on and talk about the widely reported case of the officer in Ohio, who “accidentally overdosed on fentanyl when he brushed off a powdery substance from his shirt.”

That case triggered an article in Slate magazine, The Viral Story About the Cop Who Overdosed by Touching Fentanyl Is Nonsense.

My read on that story (without any knowledge except the news reports) is that if the officer truly overdosed (suffered respiratory depression) it was from inhalation, not touching.

The LA Times story describes the police response to an overdose call: “Officers have been trained to “back off” when they come across white powder and an unconscious victim at the scene of a call, he said.”

It is unclear from the article whether treatment was delayed to the three overdose victims, one of whom died. Hopefully, medics (with proper PPE) were allowed to go right in to treat the patients.

The danger to repeated bad information is critical care will be delayed due to unwarranted fear.  The spector of pile of fentanyl powder suddenly morphing into a devilish cloud that strikes down a brigade of responders is science fiction.  Leave the powder be, wear PPE and take care of the human being in respiratory depression.

“A woman and three children were also found in the 800-square-foot apartment and removed, Bertagna said. They, along with the officers and paramedics, all underwent decontamination, essentially an intense shower.”

Is this going to be the new standard after every overdose call?

The next day, the Wall Street Journal had a front page article: Fentanyl Isn’t Just Deadly for Drug Users: Police Are Getting Sickened.

The Journal article was fascinating in its detail of how the fear of the drug has transformed the way everyone from local cops to medical examiners to prosecutors handle their business.  The Journal, which made no mention of the toxicology paper, cited not only the case of Ohio officer, but the Maryland officer who had Naloxone sprayed into his nose while he was still conscious and talking.  They never bothered to attach the atomizer because they were so panicked that there wasn't time to save him.  Needless to say, he did not meet guidelines for the administration of Naloxone.

Md. Officer Recounts Exposure to Heroin, Fentanyl on Overdose Call

While it is hard to comment on actual calls, when all we have our newspaper accounts, which can be inaccurate, all we can do is comment on the account.

There is clearly an atmosphere of fear in these articles and accounts that feeds into hysteria.

The LA Times article cites the officer reciting the mantra from the DEA’s document that when you see powder and a cyanotic patient, you step back.  The DEA, in their Fentanyl: A Briefing Guide for First Responders, writes:

Personnel should look for any cyanosis (turning blue or bluish color) of victims, including the skin or lips, as this could be a sign of fentanyl overdose caused by respiratory arrest. Further, before proceeding, personnel should examine the scene for any loose powders (no matter how small), as well as nasal spray bottles, as these could be signs of fentanyl use. Opened mail and shipping materials located at the scene of an overdose with a return address from China could also indicate the presence of fentanyl, as China‐based organizations may utilize conventional and/or commercial means to ship fentanyl and fentanyl‐related substances to the United States.

The Journal article at least cites an officer who while recognizing this, says, “If someone is there not breathing no police officer I know is going to spend five minutes putting on personal protective equipment.”

My fear is that some responders will delay helping critical patients to put on excess PPE (Think ET) or call in Haz Mat teams, when all they need is gloves, and an N-95 mask, which takes only moments to put on.  Delay in treatment caused by unnecessary fear will cost human lives.

On July 30, an article in the Eagle-Tribune, Mass. Fire Chief Seeks Improved Protocols for Opioid Overdoses, describes a town spending $75,000 on a hazmat response to a scene where three people overdosed.  The article includes the line: “The fear on Garden Street that morning was the men had overdosed on either fentanyl or carfentanil, an even stronger man-made opioid that can be toxic to someone merely in its presence.”

There is no scientific evidence that fentanyl or carfentanil are toxic to anyone who is merely in the same room as the drug.  The danger is inhalation or injection.  If you wear proper PPE, there is little risk in treating your patients.

To his great credit, the local Fire Chief asks the state for improved guidance on how to handle these situations.

"I definitely think this needs to be reviewed... It's always safer to have an abundance of caution than to ignore it. But we need to work on the future of how we are going to handle this," Moriarty said.

He explained that for years firefighters have used universal precautions—gloves, masks and eye goggles—when they respond to medical aid calls, including reports of overdoses.

Now, when are those universal precautions sufficient? he asked.

The American College of Medical Toxicology and the American Academy of Clinical Toxicology's joint statement on "Preventing Occupational Fentanyl and Fentanyl Analog Exposure to First Responders" states “the risk of clinically significant exposure to emergency responders is extremely low.”

What is the logical extension of the DEA's reasoning?  There are millions of addicts in the country who inhale and inject powdered heroin and/or fentanyl multiple times a day.    Are they all walking hazmat scenes? Could they have grains of powder in their clothing? Does this mean that if you have a history of heroin use you, on entry into an ambulance or hospital, will be treated like a potential Ebola patient, requiring isolation rooms, decontamination and health personnel donning and doffing high level PPE?  All because of the misguided belief that touching the powder can kill.

It is time for the national emergency physician organizations and state EMS offices to speak out on the debate and hopefully end the hysteria before it truly gets out of control.

Stay safe.  Wear your PPE.  And take care of your patients.

 

Saturday, October 07, 2017

Endocarditis

 The patient is "a skin popper."  She injects heroin into her skin rather than snorting it or injecting it directly into her veins.  Her arms are covered with sores in various stages of ulceration from old scars to open weeping sores. 

example of skin popper
The ambulance crew is there not for an overdose, but for chest pain and confusion.  The medic puts  electrodes on the woman's chest and does a rapid 12-lead ECG.  The ECG shows huge anterior ST-segment elevations.    The 12-lead is transmitted and then a STEMI ALERT is made to the receiving hospital.  The cath team meets the patient at the ED door, but the doctor is concerned that the patient is having difficulty comprehending the consent instructions and is unable to write her name.  She is sent to the CT scan before being rushed up to the cath lab.  A Stroke Alert is called and as soon as the cath lab team has pulled several emboli out of her occluded left anterior descending artery, the neurology team takes over.  The CT scan revealed multiple septic emboli in the brain as well.  Septic embolic are small emboli filled with pus and bacteria that likely broke away from the vegetation in the patient’s heart values.  The patient suffers, like many drug users who use dirty needles, from endocarditis.  If her heart were a carburetor, the mechanics would throw it out rather than attempt repair it it is so gunked up.
 
 
[caption id="attachment_13629" align="alignnone" width="300"] http://circ.ahajournals.org/content/107/20/e185/F2[/caption]

Bacterial Endocarditis

Endocarditis is epidemic in the United States today.  It’s rise mirrors the rise of opioid deaths. While this patient’s demise will not be counted in the overdose death numbers, she is nonetheless a casualty of the opioid epidemic that is destroying people, families and communities across the country.  The woman is very sick.  Too much damage has been done to her heart and brain.  After a discussion with her loved ones, she receives a final opioid -- morphine, then she is extubated, and with family at her side, she passes on. 

 
 
***
 
Endocarditis can come from using dirty needles.  Tell your patients where they can get clean needles.  In Hartford, they can go to the needle exchange van.  Here is the schedule:
 
Monday - Friday
  • 7:15 AM - 9:45 AM (Park & Hungerford St.)
  • 11:00 AM - 12:45 PM (Albany Ave. & Bedford St. by CHS)
  • 2:00 PM - 2:50 PM (Park & Hungerford St.)
They can also contact the Greater Hartford Harm Reduction Coalition at  860-250-4146.
 
 In Connecticut, users can purchase 10 syringes at their local pharmacy for about $4.  They do not need a prescription.

Thursday, October 05, 2017

Non-Opioid Pain Management

 


The state of Massachusetts just passed an emergency protocol change requiring all paramedic ambulances to carry non opioid pain management alternatives, including Ibuprofen PO, Acetaminophen PO and Ketorolac IV or IM.  Acetaminophen IV is optional.  The changes are to take place January 1, 2018.

Massachusetts Pain Management Protocol

Emergency Non-Opioid Pain Treatment Options Update

Here is the dosing regime:

Adult

Acetaminophen 1000 mg IV or PO

Ibuprofen 600 mg PO

Ketorolac  15 mg IV or 30 mg IM

Pediatric

Acetaminophen 15 mg/kg IV or PO to max 1000 mg.

Ibuprofen 10 mg/kg PO to max 600 mg.

Ketorolac 0.5 mg/kg IV or IM to max 15 mg.

The Massachusetts protocol includes the following note:

All pain medications have contraindications-do not administer medications in

such circumstances. These contraindications include but are not limited to:

Ketorolac and ibuprofen are contraindicated in head injury, chest pain, abdominal pain,

or in any patient with potential for bleeding, ulcer, or renal injury; likely to need surgery

Acetaminophen is contraindicated in patients with liver failure. Ketorolac and ibuprofen

are contraindicated in pregnancy.

Many states, including Massachusetts and Connecticut, have been passing laws allowing patients to fill out non-opioid directive forms.  This will allow patients who want to avoid opioids a pain management alternative beyond ice and splinting.  I have had many patients decline opioids, ranging from patients in recovery to  patient to others fearful that “Fentanyl” will send them down the road to addiction and death.  While those fears are largely unrealistic in the context of fentanyl being used for an acute painful injury, avoiding opioids if there is another alternative is probably not a bad idea.

I was not even aware that Acetaminophen  could be given by the IV route or that it was considered as effective as morphine, but a recent randomized controlled study published in Trauma Monthly showed it was safe and efficacious and even outperformed morphine in the trial.

Efficacy of Intravenous Paracetamol Versus Intravenous Morphine in Acute Limb Trauma.

One drawback to IV Acetaminophen is its price -- $36 for a one dose 1 gram vial, compared to $2.40 a dose for fentanyl or morphine.  As it so often seems, the price of a suddenly popular drug seem to suddenly skyrocket.

When IV Acetaminophen Prices Suddenly Skyrocketed

IV APAP Works, So Why Don’t More EPs Use It?

Our Regional Medical Advisory Committee will be considering a similar protocol when we meet next week.  In our area, the cost of IV acetaminophen might be mitigated by the savings of not having to take an ambulance off-line for controlled substances exchanges at a hospital pharmacy every time they use Fentanyl or Morphine.

Thursday, September 28, 2017

The Opioid Epidemic: The EMS Role (Free On-line CME)

 The Connecticut Office of Emergency Medical Services (OEMS) in conjunction with UConn John Dempsey Hospital has just released a free 1 hour on-line EMS CME: The Opioid Overdose Epidemic: The EMS Role.

The auto-narrated program discusses the background of the opioid epidemic, Connecticut death statistics, Connecticut CORE initiative, the science of addiction, the dangers of fentanyl and fentanyl analogs, opioid overdose treatment, provider safety, prevention initiatives, data collection, harm reduction, and stamp bag recognition.

It can be accessed here:

The Opioid Overdose Epidemic: The EMS Role

You will just need to create an account with Train Connecticut, which is quick, easy and free.  On completion of the course you will be able to download a CME certificate.

Sunday, September 17, 2017

Testing for Fentanyl

 Across the nation harm reduction workers are going out in the street, meeting heroin users face to face and testing their powdered drugs for fentanyl.  They are not afraid because they know that touching fentanyl cannot kill you.  They do take precautions.  They wear nitrile gloves when they dip the tester strip into the powder.  If one red line comes up instead of two, the powder contains fentanyl.

Fentanyl Test Strips

“Be careful,” the harm reduction worker warns the user.  “Put two in the cooker instead of five.”

They take the user's dirty needles and exchange them for clean needles.  If the user doesn’t have Narcan, they give them a kit and the training on how to use it.

“Be safe, brother,” the worker says.

“God bless,” the user answers.

In Hartford, harm reduction workers report most of the bags they test contains fentanyl.

Greater Hartford Harm Reduction Coalition

The latest death statistics out of the Connecticut Medical Examiner’s office confirm this preponderence of fentanyl.

Connecticut Accidental Drug Intoxication Deaths Office of the Chief Medical Examiner

For the first time fentanyl was found in more deaths than heroin.  In first six months of 2017 80% of the accidental drug overdose deaths in Connecticut that contained heroin or fentanyl contained fentanyl, while only 64% contained heroin.  44% contained heroin and fentanyl.  36% contained fentanyl without heroin, and 20% contained heroin with no fentanyl.

 

Chart: P.Canning

Thursday, August 31, 2017

Connecticut Opioid Deaths Continue to Rise

 539 people in Connecticut died of accidental drug intoxication deaths during the first six months of 2017, which projects to 1078 for the year, an increase of 17.5% over 2016, according to the state Medical Examiner’s Office.

Fentanyl continued to fuel the rise in deaths.

Fentanyl was present in 322 deaths during the first half of 2017, which projects to 644 for the year, an increase of 34% from 2016.

(Graph: P.Canning)

Fentanyl was present in more deaths than Heroin.

Fentanyl was present in 322 deaths in the first six months, projecting to 644.

Heroin was present in 257 deaths in the first six months, projecting to 514.

Heroin and Fentanyl together were present in 177 deaths, projecting to 354.

Heroin without Fentanyl was present in 80 deaths, projecting to 160.

Fentanyl without Heroin was present in 145 deaths, projecting to 290 deaths.

(Chart: P.Canning)

No end in sight.

Full data can be viewed here, including all opioid and other drug deaths.

Connecticut Accidental Drug Intoxication Deaths Office of the Chief Medical Examiner

Wednesday, August 30, 2017

Katrina Journal: What's Important

 In view of Hurricane Harvey and the rescue efforts now underway, I am posting notes from my journal when I was posted in Gulfport, Mississippi in the aftermath of Hurricane Katrina.

Day One: Waiting

On the morning of September 17, we meet at the office and a chair van driver takes us up to the airport. There are five of us: two medics, two EMTs, and a mechanic. When we go through the ticketing the airline agent puts a red mark on our tickets and says, we're all special. I am thinking, isn't this nice. They are recognizing our efforts and are going to be upgrading us to first class or maybe giving us complimentary access to the VIP lounge while we wait for the flight.

When we go through security, we find out what the red mark means. We have been tagged as security risks (probably because we bought our tickets at the last minute). We stand with our feet spread, arms held out while we are beamed with electronic wands, and then frisked, and have to watch as they painstakingly go through every item in our bags.

The flight is uneventful. We are met at the airport by two company employees in a big yellow school bus. We find out both of them lost everything in the storm. The guy driving the bus has a tee-shirt that says "Everything is Good." The young woman tells us that the storm in their area hit rich and poor alike. People have empathy for each other.

As we head to the coast we begin to see the effects. At first it is just a few bent trees, some blue tarps on roofs, torn highway signs. We see a WA MART, a Burger King underneath a sign that has been blown out. The traffic is brutal as some regular bridges are out. In the water we see what was once a railroad bridge, but is now just unconnected trestles. We see uprooted trees. Boarded up stores. Some stores have "Open" painted on the boards or whitewashed wre windows remain. We see stores with caved in roofs. A motel appears open, but several rooms have no doors or windows. We go by a marina where a shrimp boat sits up on top of the supply store. It is not a sign boat, but a huge working shrimp boat. The woods are scattered with lumber and trash. We pass a large shopping center and see huge tents with a line or people standing outside. Small trucks pass us loaded with supplies, signs taped to their doors "Disaster Relief." They come from church groups. Volunteer fire departments. Some are just unaffiliated families who loaded up supplies from neighbors and headed South. The licence plates are from all over the US.

Another shopping center has a long line of cars in rows waiting to recieve supplies. I see pallets of food, bottled water.

People carry large bags of ice. Nearbye an entrepenuer sells t-shirts. "I survived the Big One - Katrina August 28, 2005" for $15.

We arrive at our base in an industrial park. The company headquarters has sprouted a tent city, rows of port-o-potties, decon showers, a mess, and supply areas. We are greeted and get a tour.

We are told not to drink the water. Don't even use it to brush your teeth. There are pallets stacked high with bottled water, and coolers of ice. We learn we will bunk inside in a large converted training room that now has rows of military cots. We get tetnus and hepatitis A shots, make copies of our licenses, and then are told we won't be going on the road until the next day. They are running 12 hour shifts. We will be paired with a local EMT. In disaster conditions we have full reciprocity and can practice under our own state's protocols.

It is now about four in the afternoon and they are serving dinner. I feel bad about eating without having done any work. The food is great -- steak, mashed potatoes, crawfish pasta, biscuit and turtle pie. I hear later they have hired a chef from one of the casinos that was destroyed in the storm.

I am wishing they would send us out on the road even if only for a few hours. I don't like feeling like the new guy in camp. I ask myself what am I anxious about. How different can it be? You're a medic. A call is a call. You're at home in an ambulance.

It is hot. We drink lots of water, sit about. There are people from all over the country here: California, the Northwest, Texas, Miami, Georgia, the NorthEast.

They give us tee-shirts to wear with the company logo on the front and on the back "Disaster Team Gulfport 2005."

Your car will be gassed, 02 changed, gear checked and ready to go for you in the morning, I am told. I get my shift assignment 530-1730. That suits me fine. The sooner the better.

Many people in camp are going through caffine withdrawl. I hear something about a FEMA mandate against caffine in a disaster area because it dehydrates workers. So everyone now has intense headaches. I am going to need my Diet Coke in the morning.

Day Two- Hellhound on My Trail

I sleep well thanks to the foam earplugs that drown out a room of snoring EMSers.

I shower, have a breakfast of sausage patties, poppyseed muffins and apple juice, then collect the truck keys, radio, and narc pouch(a fanny pack that included 20 of morphine and 20 of valium), then check out the gear. The ambulance has a life pack 10, a 02 bag and a medic bag with the drugs and IV supplies.

My partner is a woman with a thick Mississippi accent. I can’t make out what she is saying and when I tell her my name, she thinks I am saying something about a computer. I ask her how she fared in the storm, and she says her house made it okay, but she lost many trees. She looks tired, and tells me she overslept and had to rush to get in. She tells me a story about someone, but I have trouble following it – something about a relative wearing a life preserver to keep from drowning in a hot tub they are so drunk.

As we drive to our post, we pass a huge tent city and a sea of utility power vehicles lined up as far as the eye can see. The traffic is slow due to a convoy of Army vehicles. At least half the cars on the road are ladder trucks. We stop to get coffee and the parking lot is full of telephone repair vehicles.

Our post is in the north part of the county. The sticks. My partner says its not the best post for me to see anything. It’s slow up there and we could go all day without a call. A half hour later we get a call for an accident on a long country road and find everyone out of the cars. No one wants to go to the hospital, not even a young woman with a pretty good seat belt abrasion. We go back to our post.

We sit engine idling. Its 100 degrees and humid out. At least our AC works.

I read a book about the blues legend Robert Johnson, who was from Mississippi. He can’t play a lick, then disappears for a few years, comes back and is so good everyone believes he has made a deal with the devil to play like he does. He is the man who wrote “Crossroads,” “Love in Vain,” and “Me and the Devil.”

I watch “Love-bugs” on the windshield. I don’t know what the deal is with these two-headed insects that are everywhere. The bigger end drags the smaller end around. They appear to be two insects attached to each other at the but ends. I contemplate cutting the head off one to see if the other end will die. My partner tells me they are in fact two insects, and this is mating season. The bugs are everywhere. It is not unusual to see two or more couples going at it at the same time. The grilles of trucks that pull into the country store – a feed and saddle show -- are black with the bugs.

We get some walkup calls. A kid stepped on a nail. I ask him if he wants a tetanus shot – they give us a bag of the shots in the morning to give to anyone who needs one – but he got one yesterday from the car that was posted out there. Another young man asks me to take a look at his foot. He dropped a cement block on it two days ago. He has what looks like an infected wound on the top of his foot, and a swollen ankle. I press against the bone and he winces. “YOU need to go to the hospital,” I say. “I think it’s broken.” He just shrugs and says he isn’t done working for the day. “I’m not kidding. This isn’t going to fix itself. You don’t get care, you’ll be limping for the rest of your life.” “I got two more hours of work today. Can’t let the boss down.” He says he may go see a doctor when he gets off. A mother with a baby with a fever of 103.8 asks for directions to the hospital. It seems people are on the stoic side in this state.

We eat lunch at a gas station/food mart that has a small grille in the back. I order fried oysters, but they say since the hurricane there have been no oysters. Instead I get a fried catfish “po-boy” which is the catfish served on French bread. I also order fried okra and corn. While we are eating, two young men come in looking dazed. They are not from the neighborhood. They say they both lived down by the beach. “There’s nothing there,” one says. “Its all gawn. It’s all gawn.” They say they are living in a car.

I give the waitress a tetanus shot. Everyone else has had them. We go back out and sit in the ambulance. The sun is beating down hard now. The AC barely holding its own. On the radio, other cars are getting called. Nothing going on in our area.

There are some interesting bits in the paper. A family five miles inland has a three-foot shark in their front yard pond. The areas golf courses are chewed up, but a few have opened for nine holes. The local birdwatcher says birds are just now starting to return to the beach. The third oldest house on the Gulf Coast was completely destroyed.

The radio is reporting another hurricane brewing in the Gulf that by Wednesday should be due South of us.

At four my partner requests a post change and they send us down to a central area. The stores here are battered. On the main road, which is lined with strip malls, shopping centers and gas stations and fast food stores, there is hardly a tall sign that is not blown out. I see a chick-Filet Restaurant, which they do not have in the North. I savor their sandwiches, but they like most of the restaurants are closed. An hour passes with no calls and they send us in. Instead of going right back to the base, my partner takes me down to the shore and it is there where I see what it is all about.

The destruction, particuarly along the waterfront is astounding. Miles of beachfront homes, apartments and businesses are no longer there. Further inland homes are crumpled into piles of lumber, others with roofs torn off, windows blown out.

It wasn’t the wind, my partner says, but the tidal surge. I later hear a tale of a man who tried to ride out the store in his newly built mansion. He had to climb to the fourth floor, where in the middle of the howling a neighbor’s boat appeared, and he and his wife got in it, and when they rode out, they were above the telephone wires.

I have often fantasized that is I lived in a shore town, it would be interesting to ride out a storm, to say you had withstood a hurricane, but a force like this – my lord. I think of people whose houses exploded in the surge and of those farther inland that filled with water drowning them in a matter of minutes.

The remaining houses are spray painted with Xs by searchers, noting the time and what was found. If a number appears under the X, it stands for the number of bodies found in the home's rubble. A medic found a regular patient, known and loved by the local crews, drowned in her home. That house got a "1" under the X. They took a house sign from her destroyed home and posted it back at their headquarters with a note in loving memory of the woman they all had cared for.

No one picture could describe the devastation. The lens isn't wide enough to encompass the breadth. What you need is a video camera, and a slow drive along the beach road, recording the miles of destruction. A casino ripped in half, with one half ending up a half mile down the road in the middle of the street.

Giant hundred year old trees ripped out of the ground, crushing cars. Entire apartment complexes obilterated.

Where banks once stood were now only concrete slabs and the giant cement vaults. Nothing else. A church showing only its beams and steeple.

As we drive along the road, my local partner pointed out what was once there: a good place to get $1 breakfasts, a bar that people went to on Friday nights, an expensive condo complex, a historic home. All of it vanished.

In thinking about what kind of force could make that damage I think of Robert Johnson's famous blues line. "A hell hound on my trail."

Back at the base, they have dinner for us. They have hired a chef from one of the destroyed casinos and his lasagna is fantastic. As other crews come in from the road, I learn it has been a slow day all around. The local operation normally handles the area with 14 cars. They have had upwards of 40 on post storm. People are worried things will start to get busy as people with chronic diseases run out of their meds, and when rebuilders come in and start getting on roofs.

The schedule comes on. I’m on 9-2100, which will give me a chance to sleep until I wake up. I stay up watching the news on a TV with bad reception. The sports is all about college football. No baseball scores and only two NFL games.

Day Three - "Dooh!"/EGO

I sleep through the night. In the morning I have a breakfast of sausage, grits, biscuit and fruit.

I work with a nice 27-year-old guy from Oregon who would like to go to medical school. He has been in Mississippi going on three weeks so he is familiar with the roads.

Right off the back we are sent for a chest pain at one of the Red Cross Disaster relief centers. I have told him I am a good map person, but we shoot by the road because there are no street signs. I have to gauge by the map and what appear to be roads and I misgauge. We swing around, and the delay is only a minute or two.

The Red Cross center is in an industrial park. As we approach the road is crammed on both sides with cars for a great distance. People walk along the sides of the road as if they are walking to a sporting event. There is a huge line outside the gate, mothers carrying babies, trailed by children of varying sizes, old people holding each other up. A guard lets us in the gate and directs us toward a big open tent. Another man points us toward a table where three woman sit, none of them looking particularly well. I
ask who is sick and I am directed to two of the woman, who are both pale and diaphoretic. Their stories are similar. Both have had bypasses, one has two stents, both have been taking nitro. Both refuse to go to the hospital. The heat is over 100 degrees and sopping humid. Its just a little chest pain,” one says. “I’m feeling quite better now that I am in the shade. I appreciate your wanting to help, but I’ll be fine. I don’t want to make any trouble.”

I plead with both of them to go to the hospital, but the closest I get is calling their physician. The line is busy, the woman says, though I wonder if she has not dialed her own cell phone number. While I am talking to one of the other women, the other woman says. “Doctor, I’m feeling fine really. I had a little chest pain, but its over, what you want me to come to your office, after I’ve got my check, well, twist my arm, okay. Bye.” I have turned now and am asking if I may talk to him, but she shrugs and says “Sorry. I hung up. We both are going to see him later when we’re done here. Thank you for being so nice and caring about us.”

Just then, a large man profusely sweating man is being lead over by two others. He is only 37, but he has a history of an MI. he too has been gobbling nitro. “You can check me out,” he says, “But I ain’t leaving until I get my check. I waited sixteen hours yesterday. I’m not leaving.”

Nothing works, I make every appeal possible. Think of your family, think of the future. I don’t want to come back and have to pound on your chest. No go. He isn’t leaving. After giving them all aspirin (and doing 12 leads) we end up with three refusals, and a probably empty promises that they will call if they start to feel worse. The nurse has asked us if we can post a unit at the center. My partner tells me there are relief centers like this all over town with lines as long. I tell dispatch I think we will be sent back here and they have me talk to a supervisor who says he will look into it. I think you could easily lay out fifty cots and start running Ivs on all of them. Walking out there are people leaning against each other, holding each other up. The sun and humidity are brutal.

They send us to a new location, but for the rest of the day we hear other ambulances dispatched back to the center – for chest pain, for dehydration, for asthma.

We are dispatched to another Red Cross center. This line is just as long. This one has an army medical team assigned. We are the second of three ambulances –all arriving lights and sirens for unknowns within ten minutes of each other. An army medic gives us a quick briefing. We have lots of dehydration. We’re in there starting lines. Just go in and help us triage, take the worst ones, and send another ambulance in. It’s getting out of control. The scene is surreal, people in fatigues, crowds of people, a helicopter sweeps low overhead. We go in, and a woman in fatigues says, "We have a baby who isn’t responding. She’s been in line since six thirty this morning. I put an ice pack on her and she doesn’t flinch." I see the baby, and snatch it from the mother. I give it a little pinch and it doesn’t respond. “Let’s go,’ I say. It is too crowded and chaotic in there to do a full assessment. One ambulance crew is loading a large sweating man on their stretcher, the third ambulance is just wheeling their stretcher in now. I’ll let them triage, I’m taking the kid. We race out to the ambulance and I have my partner hang a buretrol, then get in the front and drive. I strap a tourniquet around the kid, but I see no veins. I hold a 24 in my hand, but I don’t have faith to stick. I get out the glucometer, and poke the kid’s ear. Oh, to hear the noise. She wakes up and starts crying like a banshee. Now kids freak me out, and I always want to be safe rather than sorry, but I am regretting that I did not do my patented grab a piece of their skin near their belly pinch and twist hard when I first held her. I was freaked out by their setting. This is just a kid who was tired and sleeping soundly, and who really isn’t very sick. It is certainly no longer an unconscious child. I feel silly at the hospital explaining that I think the kid in fact is really okay. Now that we are in the air-conditioned hospital, and the baby is safely in his mother’s arm, the baby stops crying and seems quite normal. Baby and mother are sent to the waiting room.

Our next call is for an MVA. We arrive to find a woman lying in the middle of the road. The fire department is already there and they have put a collar on her. She is alert, and seems okay. When her air bag went off, the she got out of the car, but then lay down in the road because she thought that was the thing to do. I get the stretcher and wheel it over. I look for the release to lower it, but I can’t find it. I nod to a cop on scene and ask him to take the head end, while I pull the foot release and we lower it down. We get the woman c-spined, and over onto the stretcher. I am at the head end now, and a firefighter is at the foot end. Ready to go up I say. He pulls the release and I lift up, but the wheels don’t drop. “You have to pull the release," he says. I look at my end and there is a release there too. We both pull our releases and the wheels finally drop. My partner has to show me how to put the stretcher in the ambulance. The head end has to go into a load position, then a latch is pulled, then the foot end, pulls a lever and the stretcher is pushed in. Boy do I feel stupid. I have never seen a stretcher like this before. The worst part is my partner asked me in the morning if I knew how their stretcher worked. My internal answer of “Daah!” in the morning turned into "Dooh!" when I had to work the stretcher. You learn something new everyday.

Next we are sent to another hospital to pick up a man who has been having increased confusion and falls for a week. They did a CAT scan and it showed he has a subdural hematoma. One of his pupils has just blown. He needs to be transported to a distant hospital where they have a neuro ICU. He is a 73 year old with a thick Mississippi accent wearing a white tank top tee shirt. Between his accent and his confusion, I have a hard time carrying on a conversation as we race along the highway.

On the way back, we stop at a highway rest stop to get a hamburger. Gas is a little expensive down there.

We're posted in the outskirts off the highway. A guy approaches us and asks us if we have any glucometer strips. He is a nurse with a team who's job it is to check on the welfare of other nurses working in the disaster area, and they have a diabetic nurse in the hotel there who isn't feeling well. They have glucometers but no strips. His glucometer isn't compatabile with ours so he ends up asking if we wouldn't mind going in and checking on the nurse with him. We bring all our gear, including the glucometer and the heart monitor. There is another nurse in the hotel room with the nurse who isn't feeling well and she is somewhat offended by our presence. I go to take vitals and she says she has already done that. She tells us she has fully assessed her, she is a nurse and all she needs is the woman's blood sugar checked. My partner and I both have the impulse to slam her, but we don't. I think we handle her with respect, while still doing what we need to do. There is no sense in getting into pissing fights when the goal is to just help people. The ill nurse refuses transport. I have the offended nurse sign the refusal as a witness. She puts a lot of letters after her name.

We go to a waffle house to use the rest room, and end us in a conversation with a retired army chaplain and his wife. The chaplain, who wears an oxygen cannula has come down from Michigan on his home to help counsel people. he starts telling us about World War II, while his wife sits there patiently. We hear about the time the Germans came over the hill at them. We shake his hand, compliment him on his life and his heart for coming down to help people, and then make our exit.

I start to think about the issue of EGO and what motivates us to "do good." Why am I in Mississippi? Is it because I am "good person" or is it because I want to be able to tell people I went to Mississippi so they will gather around and hear my stories? Am I pure of heart or does my heart have other motives? And does it really matter what your motives are if you are doing the work? I always want stories. I like to be able to say "There I was!" When I was a kid one of my favorite cartoons was Commander McBrag. His catch line was "There I was tiger in front of me, lion to the left, a band of savages attaching from the rear, an alligator filled swamp on my left."

At the camp one night there was a big debate over people who come for the wrong reasons. One person said they came because they wanted to help people, not because they wanted to say they were there. I don't think the reasons you do what you are ever so clear cut. On one hand we can puff out our chests and say we are here helping the victims of the hurricane out of the goodness of our hearts, which we are, but at the same time we are not volunteering in the strictest sense. We are getting paid to be here. Few of us asked what we would be paid or how we would be paid when we volunteered to go. I would have gone for nothing (as when I went to the Dominican I paid my way). But even if I wasn't being paid, it wouldn't be for nothing, because I would be getting experience in return, and experience to me is as valuable as money. I also go because it makes me feel better about myself. Would I go if it made me feel worse? There is some hardship in leaving your life at home for a week and sleeping on a cot in a room full of snoring people, but it is only a week.

The people who impress me the most down here are not the people from FEMA or the Red Cross or the ambulance or the utility workers, it is the common people -- individuals or small groups who have collected supplies from their neighborhoods, loaded up trucks and come down and passed the stuff out -- food, water, clothing, even money. No bureacracy, no processesing or paperwork, just getting the work done. There is a purity there that I admire.

Our company has a plan where you can donate some of your unused paid time off to fellow employees who are sick or suffering hardships. I have never done it. Maybe I should. I definately should. I should do it and not tell anyone, except whoever I need to tell in order to do it.

I admire anoynmous donors.

It is sort of like the old saying If a tree falls in the forest and no one hears it, does it make any noise? Of course it makes noise.

I read an article in USA Today about the guy who founded Domino's Pizza, then sold it for $1 billion. The guy gave up his yachts, his mansions, his rich life, and has very quietly been living a simple life, and giving all his money away to charitable causes, and giving it away without fanfare.

What would most churchgoers do when faced with this decision? Every week, you put a twenty dollar bill in the collection plate as all your fellow church goers look on. You have the choice now, of giving God or whoever $20 on the sly, which he will match also on the sly with the only sticking point being when the plate is passed to you, you have to pass it to the next person without putting any money in. So the church is getting $40 instead of $20 because of your choice, but all your neighbors now think you are a cheapshake, but you can't tell them why you don't put anything in. What do you do? It should be an easy choice.

I'm working on trying to be the best paramedic I can this week, and aside from screwing up with the stretcher, I feel I'm doing okay. I am being excellent at using my name and the patient's name. I am also slowing down my talk, which I think is a good idea. Years ago I was a telephone soliciter for a national company, and when I would come to work each day, I'd get a new list of numbers to call. Some days I called people in big Northern cities like Pittsburg, others, I'd call customers in small towns in the South. I learned that what worked in one place, didn't always work in the other. In Pittsburg I used my best rapid fire TV/used car salesman voice "LetmetellyouDaisyHaveIgotaDEALforYOU. IamofferingyouTWOthat's rightTWOTWOsilkpillowsforthepriceofONLYONE. If I used that voice in the the small Southern towns they would hang up on me. I had to slow it down. "Well, hello...there..Daisy...How are you...this fine morning...Let me tell you why I am calling."

In addition to trying to talk slower, I am asking myself in each situation, what does this person need from me. How can I leave them better than when I found them? The old chaplin in the Waffle House. We listened to his story about the Germans that he has told a thousand times, we complimented him and his wife. We tried to show that we valued him and appreciated him, then we left before he could tell us another story.

Dinner is over before we get back, but they have set aside meals for the later crews. Tonight there is pork and it is good.

I have no trouble falling asleep.

Day Four - Oh Well/Mississippi?

I heard someone say the other night that while there are some regional differences, a paramedic is basically a paramedic and the practice is pretty much the same everywhere. I agree, but also part of being a paramedic is being comfortable with your equipment, with your setting, with your routine. A good paramedic can improvise, but it does help to have a certain underpinning like a captain who knows his boat and his area of the sea.

First call is for an unknown. The fire department arrives at the church before us and we find them grabbing a skinny woman who is screaming "Its a lie! Its a lie! I didn't kill myself. I didn't kill myself!" She is out of her mind. I hear someone say she has been smoking the stuff. The firefighters who are both big men, walk her out to us. She is fighting and now starting to spit. They throw her down face first on our stretcher. I announce that I want to sedate her. One of the firefightres says we are close to the hospital. Maybe ten minutes away. The woman is creaming spiting and trying to bite. "Let's get her in the ambulance and I'll sedate her," I say.

Under my protocols, I would give her injections of Ativan and Haldol and in two minutes she would be snoring. The gear in Mississippi doesn't have Ativan of Haldol. All I carry here is Valium. The problem with Valium is I can't give it IM, I have to give it IV. An additional problem is they don't carry saline locks, so if I want to give the patient Valium, I have to hang a bag of Saline. Whiule my partner spikes the bag, I put an IV in the back of her arm while the fire guys hold her down as she continues to buck and shout and spit and try to bite. He hands me the line, and I try to take it down -- they have no Veneguards. The poatient is diaphoretic, the tape sticks to my gloves. I finally get it taped down. I draw up the Valium, put it through the rubber port, then open up the line. It won't run. I know my line is good, but I can't get the fluid to run. I examine the drip set -- it is foeigh nto me. The roller clamp is above the drip chamber. I try to trouble shoot, but can't get it to run. I then have to find a syring, drwa up some saline and flush the the Valium in through the rubber port. It flushes fine, but still the line won't run. The next thing I know the IV has been ripped out in the patient's flayling and the Valium I did get in doesn't seem to have made any impact. We finally get to the hospital where they give her Ativan and Haldol and there she is sleeping like a Baby. I examine my Valium and discover
I only gave her 2 milligrams instead of 4. I was expecting to give up to 10 depending on how she reacted. My mistake comes from the fact the Valium is stored in a syringe similar identical to the morphine we catrry back home and here in Mississippi. Execept the morphine is 10 milligrams in 1 cc, the Valium in 10 milligrams in 2 ccs. In the heart of the battle, I thought I was drawing up 4 mg, but in fact I was only drawing up 2. Not enought bay any means to sedate a person.

Oh, well.

At the hospital I beg the nurses to give me some saline locks and they are happy to oblidge. I want to ask for some ativan and haldol, but don't think I will get anywhere with that request.

We do a chest pain, which I think is just an anxiety -- a local business owner under stress. He thanks us for helping him. His ECG looks good, his skin is warm and dry, good vitals. He has had similar pain and be told by his doctors it is stress. Two nitro don't help. I work him up, give him some aspirin, some 02, but stop the nitro after two.

We do a psych -- an 18 year old who has been told to move out by his adoptive father. The cop tells me there are some 10-80s in the family. I think he means some of the family died in the storm, but I am told later that 10-80 is local slag for an AIDS patient. Eighty. AIDy.

The last call is a fall at the airport. A man who has been obviously drinking has taken a tumble down about ten stairs. The fire department has a c-collar on him. We board him and get him out to the ambulance. The man has no idea why he is in Mississippi. He claims no knowledge of the hurricane. I look at his license and the photo there is one a bearded madman. One eye closed, the other cocked wide. He looks like he has just beat his wife, kicked the dog, downed a fifth of jack Daniels and walked into a pool hall ready to fight.

I don't know if he has a concussion or is just completely hammered, but I work him up. He knows his name, social security number and home addresses, but he has no clue why he is in Mississippi. "Mississippi?" he says. "What am I doing in Mississippi?"

***

It takes forever for us to get from the hospital back to the base. The traffic jams are horrendous with so many roads closed. In the passenger seat, it seems like I fall asleep, open my eyes, and we're only ten yards down the road. I fall asleep again, open my eyes and we are still not through the light.

***

At dinner we talk about the new hurricane, Hurricane Rita that is headed into the Gulf. One of the local guys, who lost everything in Katrina says he hopes it hits us. "Everything is already destroyed here. No one should go through that."

Day Five - Such a Storm

I tell myself no surprises today. I get in my ambulance an hour early and check it out from top to bottom, then set it up the way I want it. I am pleased to find this ambulance has Haldol in its jump kit -- a day too late. The ambulances are from many states as is the gear, so each day is an adventure in what you will have to work with. While the Haldol is the good news, the bad news is the intubation kit only has the crappy disposable intubation blades (We tried them a few years back and had several cases of the blades bending) and an old Life Pack 10 lacking even the hands off pads. If I have to shock someone it will be the old fashioned way, lubing up the paddles with gel, and pressing them hard against the chest. BAM! I do confess I liked doing it that way.

Our first call is to one of the relief centers where we were at two days before, the one with the army people. I get an awesome report from the army medic, top to bottom assesment, history, almost down to the color of the patient's last poop. I complimented the medic on it. I was very impressed. The patient is an obese woman in her late sixties with some breathing difficulty. She is supposed to be on oxygen at home, but since the storm has had no power, consequently no oxygen. She also has been out of her inhaler. I give her a treatment and she is doing much better. As we go to the hospital we have a bit of a dialogue, though I have a hard time understanding her deep Mississippi accent. Here's about what it sounds like:

##############Since I was a chile##############such a storm################our boys over there######that man.#######################Thought I'd never see the day#################################It done takes the cake.####

***

More traffic. Unbelievably slow.

***

We get called for a guy who fell off a roof. These calls have been going out all day. There is hardly a roof that doesn't have someone up on it, working to repair or replace it. The man has fallen through the roof and landed on concrete twenty feet below. He may have had a brief period of unconciousness, but he remembers falling and is complaining of pain in his side and back. He has some welling and redness on his left flank. When I palpate his pelvis he feels pain and he can't lift his legs without pain, although he is able to move them. I find it curious that he already has a c-collar on while we are the first unit there. We c-spine him, and take him on a priority to the hospital. He is grey, clammy and has a pressure of barely 90, yet he is thanking me for coming down to help, and asking me where I am from. A little poke, I say, as I put a 16 in his wrist. That wasn't a little poke, he says. Sorry. He keeps his good manner.

It turns out he has a broken pelvis, broken ribs, and later a hemothorax. My partner solves the mystery of the c-collar. It seems a fire truck came by, ran in, put a collar on the guy, then said they were actually on another call and help would be there soon. Interesting.

We get sent on a priority one for an unknown and I don't know whether they have us in the wrong area or all the other cars on on calls, but it takes us 40 minutes to get there through the traffic, through my misreading the map (our map books were by quadrants, so you had to keep flipping pages), and one street sign turned around pointing the wrong direction. Anyway, it turns out to be a psych. He is bipolar and we have quite a conversation. He is down on a mission to help people, but claims his partner is holding all the cash and he hasn't been able to afford his meds. I'm sure his partner has a different story. He is from Boston and we talk about the Red Sox and before the ride is over I am assured he is personal friends with half the most famous sports figures in New England History.

Our last call is for a possible stroke. It is a small ranch house on a street just a block or two from other streets where all the houses have been destroyed. We find a woman in her forties sitting in a chair like she is paralyzed. Her mouth is shaking, her eyes look very scared, and she is crying. She seems very spastic. But her pupils are equal and reactive, her skin warm and dry, her grips equal. She can answer me in brief words, that are not slurred. The neighbor who called us said they were talking about their lives and they were both crying, and then suddenly she started acting wierd. She tells us the woman's boyfriend in on an off-shore oil rig. There is a new hurricane, already named Rita that is threatening to be as big as Katrina. I don't know what to think. The woman's pressure is good, but her heart rate is in the 140's. I'm guessing it is some sort of psychological episode, but I work her up anyway. IV, 02, monitor. At the hospital, when I walk by her room, she follows me with her eyes.

We have spaghetti for dinner. Every one is talking about the hurricane and where it will hit. It is projected for Texas, but one big turn to the right and it will right at us. "I hope it hits us," one of the guys says. He lost everything in Katrina. "We're already destroyed. No one else should have to go through that."

There is talk of moving some resources to Texas. I think about what the company has set up here and I have to hand it to them. I don't know

what kind of arrangements they have with FEMA, but whoever is in charge of seeing that things get done in Mississippi, can easily put a check mark by EMS and say, "We got it covered."

Day Six - Resiliency

I have breakfast with one of the guys from another division in our state who came down a day before I did. We talk about how a trip like this can change you. Any time you can get outside your normal life, it can't help but make you different.

What impresses me is the resiliency I see in people's eyes and their voices. You ask people for their address and they say, "Where I used to live? or where I'm staying now?" Maybe they haven't hit the angry portion of the grieving process or maybe they have just blew right on by it. I imagine what I would think if I saw my house flattened into a timber, a mound of wet irrecoverable junk. What would I grieve for -- a crushed car? a smashed computer? a lifetime of collected books ruined by water and mud? Seeing it all piled together makes me see how little material possessions mean. These people have made it through their darkest of storms, and in the morning, they look at their homes, and what they see rising out of the rubble of their old lives is their families, their grandparents, their mothers and father, their own children. "I lost everything, but my family made it through, praise mercy." I hear that over and over again. "My family made it through."

Another thing that has impressed me is the kindness people have showed us. EMS people often complain this is a thankless job, but I have never been thanked more than in this last week. From patients to store clerks to people on the street, thank you was all we heard. It made you feel good about your life's choice of work.

I'm glad for the opportunity to come down here, and I hope more of my fellow employees will get to come in future weeks.

I work again today with the guy from Portland, which is good because he's a nice guy and I like having a regular partner. We are posted down by the water. There is a good breeze blowing, and I try to imagine what it would like to sit there in the ambulance as a hurricane came in. I imagine the ambulance being picked up and whisked away like Dorothy in Oklahoma, ending up miles away in a big tree.

We examine the Treasure Bay Casino or what's left off it. It looks like a true shipwreck.

We park next to what once was a Burger King -- only there is nothing there but one table and chair.

It is surreal down by the water. The area is blocked off by razor wire and then only let down rescue personnel, construction workers and residents looking to go over the shambles of their homes. It is not uncommon to see rescue workers walking around with cameras talking pictures of the destruction like we are in some living museum. I have so far resisted talking any novelty pictures. There is a miniature golf course where someone has put Humpty-Dumpty back on the wall and police and firemen line up to have their pictures taken with him. At one house that like so many is just a slab, someone has set up a porcelain toilet. I have heard of people having their pictures taken, pants around their ankles, reading a newspaper as they sit on that toilet with all the outdoors around them. I have such mixed feelings about taking any pictures at all. I put my camera away, but then fifty yards later see something so amazing I have to take another picture. I waver between respect for what happened and the natural human desire to laugh. I finally relent and pose for a picture drinking a Coke at Burger King.

We give out some tetanus shots, then a car drives up and worker gets out with a huge gash on his arm where he cut it on a piece of tile. We wrap it and take him to the hospital. There we talk with the nurses about the coming hurricane. They call up satellite photos and path projections on the hospital computer and give us a lecture on hurricanes that is quite impressive. It seems just about anyone who has lived ten years on the gulf coast knows enough to be an expert. They talk about the pressure systems and barometer readings and cite how Elaine bounced like this, and Ivan turned right like this. They all think the new hurricane will turn right and hit right on the Texas Louisiana border. The real tell they say is to watch the weather channel. One of the old guys on their is the one to watch. Wherever he sets up is where it will hit. Old so and so always knows where the hurricanes are going. If he comes to your neighborhood ahead of the storm, look out.

We sit around. It is a quiet day. I eat an MRE for lunch. It is very good. Jambalaya. You drop the package in a plastic bag that has some kind of heating coil in it that is activated by water. It steams the meal in just a couple minutes. The MRE package also includes wheat bread, cheese sauce, a powdered grape drink and a pack of MMs.

Around one, they call us back to the base. It seems they are going to be taking our car and sending it to Texas to get ready for the storm there. Since it is slow, they tell us to take the rest of the shift off. I want to go back on the road, but they say they have enough cars on. I'm not happy to be sitting around camp. I'm down here to respond to help, but what can you do if you don't have a car. I guess the afternoon off is good for some of the people who have been here longer than me or who are less used to working every day.

I watch them prepare the ambulances, loading them with supplies and a portable generator. Two of the people going to Texas are guys who lost everything in the storm here. It sort of a good will message. You helped us, we'll help you.

The only benefit to being in camp is they are serving fried catfish for dinner, and it is some fine eating catfish. I eat my first dinner at four, then have a second dinner at eight.

That night I talk to a woman from one of our state's divisions. She has traveled all over the world on humanitarian missions. She has enjoyed her week here, but is ready to go -- a week is enough. There are emergencies at home too. We work in an ambulance, we respond to calls. There are people coming down to replace us. There are more than enough calls waiting for us at home as well. Wherever they need us, we do the same work, up there or down here.

FRIDAY, SEPTEMBER 23, 2005
Day Seven- Gators
I am working with a local girl from Mississippi. I tell her I need a diet coke to start my morning off so she takes me to a place called Sonic, which is an old time drive-up with rollerskaking waitresses. A woman with rather fat legs on roller skates brings me a can of Diet Coke on a tray. That wakes me up.

My partner tells me how she and her partner were lost for two days during the storm, having to take refuge in first a fire station than later in a sewage treatment plant as the waters rose. At one point she and her partner were joking about how their car was going to need a little more than an "Orangeline Special" washing at the end of the day. Not long after they were wading in chest deep water as part of human chain trying to get to higher ground. She also told me about being sent into KMART in the darkness with only a flashlight to get needed radio supplies to get the communications system running, and suddenly getting very scared by a strange foreboding, and then hurrying to get the supplies and get out of the store. Later she heard that six corpses were found in the store along with four
alligators.

Outside all the shopping centers there are piles of wet clothes, the remains of donations.

I ask my partner whether people got many clothes from the donations. She says they did, but as one of her regular partners -- a large girl herself -- said. "What makes all these little itty bitty Yankee woman who ain't seen a sandwich inside the last three months think us healthy Southern women are going to be able to fit in anything they send down here?"

Our first call is for chest pain. We arrive outside a motel to find a young man hyperventilating. "He don't speak a lick of English," the firefighter tells us, then I start rattling off the Spanish with him, and they are somewhat amazed to see a paramedic talking Spanish. It turns out the guy is from Honduras and his baby sun died there three months ago. He works and sends what money he can back. This morning, all of a sudden he was having trouble breathing and his hands got very cold and he was scared. By the time we get to the hospital, he is feeling much better.

We spend most of the day on the shore. My partner takes me down to the WalMart which is now a see through WalMart.

She tells me how the security guard there always used to give them a hard time about parking in the fire lane, threatening to write them tickets. She said after the storm when they went down there, they drove right up to the fire lane and took pictures of themselves standing in front of the ambulance parked there.

By the water the wind is really whipping up as the hurricane approaches. Port-o-potties are getting blown over and knocked across the road.

We talk to a police officer who is on the lookout for waterspouts.

We give out some more tetanus shots to workers.

We do a call for a motor vehichle and find a woman with neck pain. What is funny is how down there everybody knows everyone. A firefighter introduces us to the patient by saying "This is Patty, John down at central fire's sister's cousin's neighbor's wife. She got four kids, two dogs and cooks a fine apple cobbler."

"Okay," I say, and I tell her my name and say it my pleasure to make her aquaintence, circumstances aside.

Our last call is in a poor neighborhood for a man feeling week. He has colon cancer and hasn't seen the doctor for awhile. He ran out of colostomy bags during the storm and hasn't had one one for three weeks now. His abdomen is stained with feces and there are flies landing all over him. His nail beds are white and while I can't get a pressure, he is only going at 96 on the monitor. We take him in.

The shift is over and they bring us back to the base. Dinner is country fried steak, and as always it is mighty fine.

The new people from our division have come down and I give them tips on what to expect. "Its just like up North," I say, "You do ambulance calls, except the people are very thankful and the scenery is mindblowing. And you need to play with the stretchers before you put your patients on them. You'll have a great time."

Eleven-o'clock I'm in bed.

Day Eight - The Earth

I awaken shortly after midnight. The high winds of Hurricane Rita have knocked down one of the tents where sixteen EMTs and paramedics were sleeping. We need to push our cots closer together to make room for the temporarily homeless tent people.

I am soon back to sleep, and awaken on the tired side. I have a late breakfast of pancakes and sausage. I'm on the afternoon plane out of town so there is no going on the road today. I get an early lunch of cheesesteak, macaroni and cheese spiced with crawfish and spicy sausage, and a slice of apple pie.

I am sorry to be leaving. I think it was a great experience to be down on the Gulf Coast and to witness the strength and goodness of the people as they rebuild their lives after the storm's fury.

While waiting for the bus, one of the local workers comes over and says, "Thank you for coming. We appreciate it."

He holds out his hand and we shake.

"You're welcome. I know you'd come up for us if we needed the help."

"You can sure put my name on that list," he says.

As he walks away, I call after him, the words coming to me now. "Thank you," I say, "For showing us what's important."

He smiles. "Sometimes the littlest things -- that you sometimes forget about -- are the biggest."

I understand what he means.

***

At the airport, I learn my reservation has been canceled. There was a mixup in the reservations and I was supposed to be on the earlier flight. The other nine head to Atlanta and I wait in Gulfport for four hours till I can get a later flight. To make matters worse when I go through security, they pull me out of the line and practically strip search me. It was funny on the way down, not so funny now. I admit to being tired. The guards try to make small talk, but I am in no mood. I just hold my arms up silently. My zipper makes their electric wand go off, so my crotch gets patted down with the back of a gloved hand. I know they are just doing their job. Next I stand there while they meticulously go through my carry-on bag. At last I am clear. I make a connection in Atlanta and arrive back in New England after ten. The company division head picks me up, which is nice, but after he drops me at my car and takes off, the car won't start, and I have to find someone to jump me.

Home at last, I have a cold beer and sit again in the quiet. I think again about Mississippi and also about my trip to the Dominican. I am grateful for what I have seen this year, grateful to be healthy enough to help others, grateful to be able to walk the earth.